Aluminum phosphide (ALP) is a cheap, easily available agricultural pesticide which causes lethal poisoning by liberation of phosphine and. Aluminium Phosphide Poisoning: Management and Prevention of AlP poisoning, mediated by phosphine and mechanism of action have not been established. Aluminium phosphide (AlP) is a cheap solid fumigant and a highly toxic pesticide that is commonly used for grain preservation. AlP has currently generated.

Author: Brami Faegal
Country: Turkey
Language: English (Spanish)
Genre: Literature
Published (Last): 2 June 2016
Pages: 372
PDF File Size: 8.46 Mb
ePub File Size: 4.46 Mb
ISBN: 224-3-20782-487-6
Downloads: 71607
Price: Free* [*Free Regsitration Required]
Uploader: Sahn

Aluminium phosphide poisoning

Rajendra Kumar Ghritlaharey, M. Previously, the laws and legislations were not that strict and it was easily available on the counter; but in the last few years stricter norms have reduced its easy availability, even though they are still not enough to reduce the suicidal rate due to its consumption, which traumatizes so many families.

Preventing phosphine poisoning and explosions during fumigation. One hour later, his cel;hos blood pressure had increased to 80 mm Hg. I wish the publisher opisoning the best in his future endeavors. Dashora UK, Swaroop D. Respiratory features may include cough, dyspnoea, cyanosis, pulmonary edema, respiratory failure and ARDS. Epidemiological, clinical, pathological findings.

Management of celphos poisoning with a novel intervention: A ray of hope in the darkest of clouds

Environmental health criteria Spot diagnosis of aluminium phosphide ingestion: Clin Toxicol Phila ; Treatment of the cardiovascular manifestations of phosphine poisoning with trimetazidene, a new anti ischemic drug. After ingestion, AlP releases phosphine gas in the presence of HCl in the stomach, which is rapidly absorbed throughout the gastrointestinal tract, leading to systemic toxic effects involving the heart, lung, kidney, liver with manifestation of serious cardiac arrhythmias, intractable shock, acidosis and pulmonary edema.


At present, the routine use of intravenous magnesium sulfate therapy is questionable with the existing literature as hypermagnesemia has also been described clephos some cases of AlP poisoning.

Studies in the past have shown increased levels of inflammatory markers cytokines and interleukins in ARDS, which increase the capillary permeability.

As each poison has a definite elimination time, so also is the case with AlP. Toxicity of exposed aluminium phosphide. A case of accidental fatal aluminum phosphide poisoning involving humans and dogs. Advertisers Access Statistics Resources Dr Archana Dambal “Journal of clinical and diagnostic research is a welcome change in publishing practices.

Commercially, it is available as dark grey tablets of 3. However, unfortunately, it is now one of the most common causes of poisoning among agricultural pesticides. J Toxicol Clin Toxicol ; However, the rational use of Magnesium Sulpahte had to be guided by serum Magnesium levels, as there have been reports of the occurrence of hypermagnesaemia 1112 The serum phosphine level of more than 1.


Acute phosphine poisoning abroad on a grain freighter. Ventilator was unable to deliver the oxygen due to very high pressures in the pulmonary poisonihg. An emerging issue among survivors of poisoning. A year autopsy experience from a tertiary care hospital in northern India”.

Aluminium and zinc phosphide poisoning. How to cite this article: J Toxicol Clin Toxicol. Histopathological changes in cases of aluminium phosphide poisoning.

Phosphorus Pesticides Aluminium phosphide Organophosphates. Open in a separate window. To progress, one needs to identify the areas of one’s weakness and to strengthen them. I appreciate the Editor, Dr. Prompt and adequate cardiovascular support is important and core in the management to attain adequate tissue perfusion, oxygenation and physiologic metabolic milieu compatible with life until the tissue poison levels are reduced and spontaneous circulation is restored.

Managing aluminum phosphide poisonings. Vascular changes may lead to marked low blood pressure that does not respond well to pressor agents.