Hence categorical use of PTP in women may lead to an under-diagnosis and subsequent under-treatment of ischemic heart disease kasl? c?plak adam sex women not caused by obstructive CAD. In this section we review both obstructive and non-obstructive etiologies of SIHD and we examine both the coronary microvasculature and epicardial vessels. Therefore, hormone therapy should not kasl? c?plak adam sex used for the prevention of CVD in women. An international multicenter prospective study on referral for heart transplantation, organ allocation and survival appears mandatory.